This course explores the structure and function of the endocannabinoid system (ECS), a critical regulatory network in the human body. Students will examine the roles of endocannabinoids, phytocannabinoids, and synthetic cannabinoids, with a focus on compounds like THC, CBD, and CBG and their therapeutic potential. The course also highlights the importance of terpenes in influencing the aroma, flavor, and synergistic effects through the entourage effect. Additional topics include chemotypes, endocannabinoid tone, and clinical endocannabinoid deficiency, providing a comprehensive understanding of the biological and practical significance of cannabinoids.